PhD position in Human Neurogenetics of Parkinson’s disease


Workplace : CRIUGM

Number of positions to fill : 1

Shift : Jour

Starting date in the job : As soon as possible

Salary : The selected candidate will be required to apply for external scholarships.

Employment status : Temporary full time

Duration : 4 years


The laboratories of Oury Monchi (PCAN, at the Research Centre of the Institut universitaire de Gériatrie de Montréal and at the Université de Montréal) and Ziv Gan-Or (NAP-Med at The Neuro and McGill University) are looking for a PhD student with an interest in clinical research in neurological disorders, bioinformatics, genetics and behavior. The successful candidate will work on a project to characterize the genetic profile of non-motor symptoms in patients with Parkinson’s disease. The student will be enrolled in the Human Genetics program at McGill University,

Parkinson’s disease (PD) is associated with a significant presence of non-motor symptoms at different stages of the disease. These symptoms include neuropsychiatric load, cognitive deficits, sleep disturbances and pain. They affect quality of life more than the motor symptoms at list in the initial stages of the disease, yet very little is known about the genetic origins of these nonmotor manifestations in PD. As a first step, we will perform a GWAS to explore associations between genotypes and neuropsychiatric symptoms in PD, and once candidates have been
identified, we will investigate how the various identified variants affect neuropsychiatric load as measured by the Mild Behavioral Impairment checklist. The project with leverage recently available data from the Canadian-Open Parkinson Network, the Global Parkinson Genetic Program (GP2), the UK biobank and other sources.

Profile sought:
• have an MSc in Systems Biology, Human Genetics, Computational Biology/genetics, or related disciplines
• Be eligible for admission in the McGill Human Genetics PhD program:
• be very motivated to learn and expand both experimental and clinical neurosciences skill sets
• Familiarity with R and Python is required.
• Teamwork and excellent organizational, interpersonal and communication skills
• Very Good knowledge of English

Duration and salary:
Funding is available for at least 4 years at rates recommended by McGill and Université de Montréal. The selected candidate will also be required to apply for external scholarships.

To apply:
Please send a cover letter indicating your interests and research experience, as well as a CV and contact details of two references to Applications will be accepted until the position is filled.


Level of study requested : Master's degree or doctorate

Written languages : french, english

Spoken languages : french, english

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